Genetic Methylation Test

Genetic Methylation Testing provides a comprehensive analysis of key genetic markers related to methylation, detoxification, neurotransmitter balance, and cardiovascular health.

By analyzing 12 critical SNPs (Single Nucleotide Polymorphisms) such as SHMT, AHCY, MTHFR, MTRR, BHMT, CBS, SUOX, VDR, COMT, MAOA, NOS, and ACAT, this test helps identify individual genetic variations that may impact methylation efficiency, hormone regulation, oxidative stress response, and detox pathways.

Understanding these genetic predispositions allows for personalized supplementation strategies, dietary modifications, and lifestyle adjustments to optimize energy metabolism, cognitive function, inflammation control, and cardiovascular health.

✅ACAT (Acetyl-CoA Acetyltransferase): Involved in mitochondrial energy production and the metabolism of ketones and fatty acids. Mutations in the ACAT gene can influence energy levels and metabolic efficiency.

✅AHCY (Adenosylhomocysteinase): AHCY is crucial for the breakdown of homocysteine, a common amino acid in the blood linked with cardiovascular disease risk. Mutations in this gene can lead to elevated homocysteine levels, potentially increasing the risk of heart and vascular diseases.

✅BHMT (Betaine-Homocysteine S-Methyltransferase): BHMT helps process homocysteine in the liver and kidneys using betaine, derived from choline. Variations can affect the body’s methylation process and homocysteine levels, with implications for liver and cardiovascular health.

✅CBS (Cystathionine Beta-Synthase): Key in the transsulfuration pathway, CBS converts homocysteine into cystathionine. Mutations can cause changes in sulfur amino acid metabolism, impacting detoxification and potentially leading to elevated homocysteine.

✅COMT (Catechol-O-Methyltransferase): This enzyme metabolizes dopamine, norepinephrine, and estrogen. Variants in the COMT gene can affect cognitive function, mood, pain perception, and hormonal balance.

✅MAOA (Monoamine Oxidase A): This gene influences the breakdown of neurotransmitters such as serotonin and norepinephrine. Mutations can affect mood, behavior, and neurological functions.

✅MTHFR (Methylenetetrahydrofolate Reductase): Perhaps the most well-known in the methylation process, MTHFR converts folic acid into the active form of folate (5-MTHF) that the body can use. Mutations, particularly the C677T and A1298C variants, can reduce the enzyme’s efficiency, impacting everything from cardiovascular health to mental well-being.

✅MTRR (Methionine Synthase Reductase): This gene provides instructions for making an enzyme that is necessary for the reactivation of methionine synthase. Mutations in MTRR can lead to deficiencies in vitamin B12 utilization and influence homocysteine levels.

✅NOS (Nitric Oxide Synthase): NOS is critical for the production of nitric oxide, a regulator of blood flow and neurotransmitter. Genetic variations can impact cardiovascular health and immune function.

✅SHMT (Serine Hydroxymethyltransferase): This gene is involved in the conversion of serine and glycine, which plays a key role in the folate cycle. Variants in SHMT can influence the distribution of folate in the body, affecting DNA synthesis and repair.

✅SUOX (Sulfite Oxidase): Responsible for detoxifying sulfite into sulfate, this enzyme's mutations can lead to issues with sulfur metabolism, affecting everything from neurotransmitter balance to cellular repair.

✅VDR (Vitamin D Receptor): Variations in the VDR gene affect how vitamin D is used by the body, influencing bone density, immune function, and overall cellular health.

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By addressing methylation inefficiencies with targeted nutrient therapy, including methylated B vitamins, liposomal glutathione, and antioxidant support, our test empowers individuals to take control of their long-term wellness, cognitive performance, and immune resilience through precision-based health solutions.